2021年妊娠合并肺动脉高压的诊治

心室充盈↓COРPVR↑?休克?呼吸衰竭Р失血?血管迷走神经反射Р静脉回流↑Р分娩Р血容量Р酸中毒Р右室缺血РInternational Journal of Clinical Practice, vol. 65, no.172, pp. 6–14, 2011Р*Р妊娠合并肺动脉高压的诊治Р*РР病理改变РNormal pulmonary arteryРAbnormal pulmonary arteryР肺动脉高压由肺动脉循环血流受限引起，导致肺血管阻力病理性升高，最终引起右心衰。大量的细胞增殖及凋亡减少使得血管管腔变小，这是造成肺血管阻力增加的主要原因，而大约20%的患者是因为血管收缩过强РCirculation.2009;119:2250–2294Р*Р妊娠合并肺动脉高压的诊治Р*РР肺内皮细胞和平滑肌细胞的相互作用РProc.2009;84:191–207Р*Р妊娠合并肺动脉高压的诊治Р*РР诊断和评估Р病史、症状及体征.?chest pain, cough, and shortness of breath. With right heart failure patients may also have lower extremity swelling, dizziness, or syncope.?血化验?BNP、 renal, liver, and neurological function will provide some information about the adequacy of cardiac function and tissue perfusion.?心电图、胸片?右心导管检查——金标准?多普勒超声心动图——assess RV and LV and valvular structure and functionР*Р妊娠合并肺动脉高压的诊治Р*