CU住院>14天患者比例Р34%?P=0.01Р整体住院期间死亡率Р27%?P=0.01Р42%?p<0.04Р缩短Р减少Р缩短Р急性肾损伤РICU住院时间Р住院时间РICU住院>3天者住院期间死亡率Р14%?P=0.06Р34%?P=0.04Р15%?P=0.04Р18%?P=0.009Р16%?P=0.05Р-60Р-50Р-40Р-30Р-20Р-10Р0РICU住院>3天者90天死亡率Р强化组与常规组比较降低比例(%)РICU患者高血糖,胰岛素强化治疗的获益РTrialРNРSettingРPrimary eРARRРRRRРOdds Ratio?(95% CI)РP-valueРVan den Berghe?2006Р1200РMICUРHospital? mortalityР2.7%Р7.0%Р0.94* ?(0.84-1.06)РN.S.РHI-5?2006Р240РCCU AMIР6-mo mortalityР-1.8%*Р-30%*РNRРN.S.РGlucontrol?2007Р1101РICUРICU ?mortalityР-1.5%Р-10%Р1.10*?(0.84-1.44)РN.S.РVISEP?2008Р537РICUР28-d? mortalityР1.3%Р5.0%Р0.89*?(0.58-1.38)РN.S.РDe La Rosa ?2008Р504РSICU?MICUР28-d ?mortalityР-4.2% *Р-13%*РNRРN.S.РNICE-SUGAR?2009Р6104РICUР3-mo mortalityР-2.6%Р-10.6Р1.14?(1.02-1.28)Р< 0.05Р* not significantРIntensive Glucose Management in RCTs?Showing No Benefit
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