症:肠壁全层慢性炎症,有淋巴? 滤泡形成。? 粘膜下层淋巴管高度扩张,有严重的淋巴水肿? 50%-70%病例肠壁有结核样肉芽肿形成Р可见类上皮细胞和多核巨细胞,但无干酪样坏死РCrohn病并发症瘘管。左边可见裂缝从黏膜延伸到黏膜下层、肌层,最终形成瘘管。瘘管可在肠袢间、膀胱和皮肤形成。累及结肠的直肠周瘘管常见。?plication of Crohn's disease is fistula formation. Seen here is a fissure extending through mucosa at the left into the submucosa toward the muscular wall, which eventually will form a fistula. Fistulae can form between loops of bowel, bladder, and skin. With colonic involvement, perirectal fistulae mon.Р显微镜下Crohn病的特点是穿壁性炎症。炎细胞(兰色浸润)从黏膜层到黏膜下层、肌层均有浸润,在浆膜表面苍白的肉芽肿中心出现结节性浸润。?Microscopically, Crohn's disease is characterized by transmural inflammation. Here, inflammatory cells (the bluish infiltrates) extend from mucosa through submucosa and muscularis and appear as nodular infiltrates on the serosal surface with pale granulomatous centers.
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