2013-4-21 会 静脉血栓栓塞症

e: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum. 2002;46:1019-1027.?Prandoni P, Noventa F, Ghirarduzzi A, et al. The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1,626 patients. Haematologica. 2007;92:199-205РaPL与VTE风险增高相关?初次发作VTE后完成6月口服抗凝治疗者:? 若aCL阳性,则再发血栓风险29%;? 若无抗体,则为14%(P=0.0013)РSchulman S, Svenungsson E, Granqvist S, et al. Anticardiolipin antibodies predict early recurrence of thromboembolism and death among patients with venous thromboembolism following anticoagulant therapy. Am J Med. 1998;104:332-338.Р系统性红斑狼疮(SLE)РSLE是一种累及多系统、多器官并有多种自身抗体出现的自身免疫性疾病,其基本病例改变是免疫复合物介导的血管炎。