plications;Befamiliarwiththekeypointsofthepathogenesisandtreatmentofpepticulcer;Tomasterthepepticulcernursinginterventionandhealtheducation;urringinareasexposedtoacidandpepsinandmostoftencausedbyHelicobacterpyloriinfection.(Uphold&Graham,2003)PepticUlcers:?Gastric&DudodenalPepticUlcers:?Gastric&Duodenalgastriculcer:ursinthestomachlining,someofthemmaybemalignant.duodenalulcer:mostoftenseeninfirstportionofduodenum.GUDUPUDDemographics(流行病学)Lifetimeprevalenceis~10%.moninmiddleagepeak30-50yearsMaletofemaleratio—4:1Etiology(病因学)Helicobacterpylori(HP)nonsteriodalanti-inflammatorydrugs(NSAID)AcidandpepsinOthersdiseasecharacteristicsChronicprocessperiodicalattackRhythmicabdominalpain