明胶和6%HESР2008年脓毒症治疗指南РFluid-resuscitate using crystalloids or colloids (1B)?Give fluid challenges of 1000 mL of crystalloids or 300–500 mL of colloids over 30 mins. More rapid and larger volumes may be required in sepsis-induced tissue hypoperfusion (1D)РSuving Sepsis Campaign:international guidelines for mangagement of severe sepsis ande septic shock:2008.Intensive Care Med,2008Р2012年脓毒症治疗指南Рinitial fluid resuscitation with crystalloid (1B) and consideration of the addition of albumin in patients who continue to require substantial amounts of crystalloid to maintain adequate mean arterial pressure (2C) and the avoidance of hetastarch formulations (1C)РSuving Sepsis Campaign:international guidelines for mangagement of severe sepsis ande septic shock:2012.Critical Care,2013Р2013 FDA对HES黑框警告
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