BV-VCA antibodies : 85% in normal adultsР80-95% of adults have serologic evidence, most infections occuring during infancy and children.РPrimary EBV infection : SeroprevalenceРIn developing countries -80-100% of children ing infected by 3-6 yrs of age ?-clinically silent or mild disease.РIn developed countries -occurs later in life, 10-30 years of age -induce clinically mononucleosis syndrome (U.S.college students : 50-75% associated with primary EBV infection)РInfectious Mononucleosis?TransmissionР“The Kissing Disease”РEpidemiology : TransmissionРIncubation period : 30 – 50 days.А(shorter in young children) РOral secretion : major role but occur slowlyРBlood products,ans : monly than CMVРIntrauterine : infrequently : if infected; no adverse fetal es and no viral transmission to the fetus.
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