etus, respiratory and metabolic acidemia, and ultimately tissue acidosis, are most likely part of a progressively worsening continuum. This is different from the adult pathophysiology, in which distinct conditions result in either respiratory (pulmonary disease) or metabolic (diabetes) acidemia. In the fetus, the placenta serves as both the lungs and to a certain degree, the kidneys. One principal cause of developing fetal acidemia is a decrease in uteroplacental perfusion. This results in the retention of CO2 (respiratory acidemia), and if protracted and severe enough, a mixed or metabolic acidemia.Р呼吸性酸中毒Р呼吸性酸中毒通常是在胎盘气体交换急性中断时发生的,继发CO2潴留。脐带一过性受压是发生胎儿呼吸性酸中毒的最常见事件。通常情况下,呼吸性酸中毒不会对胎儿产生损害。Р代谢性酸中毒Р代谢性酸中毒是在氧气供应无法满足胎儿细胞能量需要的厌氧代谢所需要的时间和幅度时产生的,代谢性酸中毒和缺血缺氧性脑病以及新生儿的功能障碍发生有关,但是即便是重度的代谢性酸中毒也不能预测继发的脑瘫。