ST活性Geng-TaoLiu,YanLi,etal.l4-inducedliverinjuryinmice.LiverInternational,2005,25(4):872-879.*小鼠肝脏ALT酶蛋白纯化免疫家兔兔抗小鼠肝脏ALT抗体制备抗体+小鼠给药后肝匀浆进行免疫火箭电泳测定肝脏ALT蛋白水平1-4:正常组82.3±6.8?5-9:双环醇组82.0±7.4?Protein:170mg/each正常和给药小鼠肝匀浆ALT免疫火箭电泳测定百赛诺不影响肝脏ALT酶蛋白含量Geng-TaoLiu,YanLi,etal.l4-inducedliverinjuryinmice.LiverInternational,2005,25(4):872-879.肝细胞保护剂对转氨酶的作用(体内)临床耐受性试验志愿者:6.25-150mg,tidx4周对志愿者血清ALT,AST活性无影响。(结果已发表在国内外核心刊物)清除自由基、抗氧化LiuGT,LiY,WeiHL,etal.l4inducedliverinjuryinmice.LiverInternational.2005,25(4):872-879.l3radicalasdetectedbyESRinlivermicrosomesBicyclol(200,300mg/kg)wasgivenorallytomicethreetimesbeforealcoholtreatment.SHcontentdeterminationrespectively.Datawereexpressedasmeans±SD(n=8).*,P<0.05,***,P<0.001vs.controlgroup;#,P<0.05vs.alcoholgroup.ZhaoJ,ChenH,LiY.EurJPharmacol.2008;586(1-3):322-331.
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