血因子缺陷PNH、PDMFVLeiden创伤与围手术期FII20210A妊娠与产褥期异常纤维蛋白原血症征制动、经济舱综合纤溶蛋白缺陷避孕药、激素异常纤溶酶原血症tPA缺乏PAI-1增加代谢缺陷高同型半胱氨酸血症多为幼年发病,反复发作,有血栓家族史。VTE:icmixedtransientVTEriskfactorsPurpuraFulminansinanewbornwithhomozygousproteinCdeficiencyFVLeiden突变?揭示西方白种人DVT的重要发病机制October23,200027-yearoldwomandiesfrompulmonaryembolismshortlyafterarrivalatHeathrowairport,aftera20-hourjourneyfromAustralia(TheGuardian,23/10/2000)AirtravelandVTEAnnualincidenceofDVTWhites 0.8-1.2x1000?HongKongChinese 0.16x1000 Liuetal,HongKongMedJ2002rateratio(vswhite)AfricanAmericans 1.27(1.07-1.51)?Hispanic 0.60(0.54-0.67)Asians/PacificIslanders?0.26(0.22-0.30)* Whiteetal,AnnInternMed1998*idiopathicorsecondary静脉血栓栓塞症的流行病学?(venousthromboembolism,VTE)总人群中VTE的年诊断率西方国家:0.5~2/1000。中国大陆:无大规模调查的流行病学数据。中国香港:0.167/1000中国人VTE发生率低于高加索人?近10年国内杂志发表的有关VTE的文章数目