《Measles麻疹》课件

inclusionbodiesCLINICALMANIFESTATIONTypicalManifestation:patientshavn’thadmeaslesimmunization,inefailurewithnormalimmunityorthosehavn’tusedimmuneglobulin1.Incubationperiod(infectiontosymptoms):6-18days(average10days)2.Prodromalperiod:3-4days?Non-specificsymptoms:fever,malaise,anorexia,headacheClassicaltriad:cough,coryza,conjunctivitis(withphotophobia,lacrimation)CLINICALMANIFESTATIONEnanthem(Koplikspots):Pathognomonicformeasles24-48hrbeforerashappears1mm,grayishwhitedotswithslight,almucosa,oppositethelower2ndmolarsfadesoonafterrashonsetCLINICALMANIFESTATIONKoplikspotsCLINICALMANIFESTATION3.Rashperiod3-4daysExanthem:Erythematous,non-pruritic,maculopapularUpperlateraloftheneck,behindears,hairline,facetrunkarmsandlegsTheseverityofthediseaseisdirectlyrelatedtotheextentandconfluenceoftherash,