异基因造血干细胞移植中实验诊断与治疗技术新进展

oS Medicine 2007;4(1):59-86Р供者选择(HLA分型)РYears after transplantРProbability of severe aGVHDРP<0.001РYears after transplantРProbability of relapseРP=0.03Р264 patients in the study were HLA-A, B, C, DRB1,?DQB1 allele matched with their donorsРPLoS Medicine 2007;4(1):59-86Р供者选择(HLA分型)РYears after transplantРProbability of TRDРP=0.17РYears after transplantРProbability of survivalРP=0.83Р264 patients in the study were HLA-A, B, C, DRB1,?DQB1 allele matched with their donorsРPLoS Medicine 2007;4(1):59-86Р供者选择(HLA分型)Р无关供者移植中MHC单倍型的研究成为HLA分型研究? 的新领域;?HLA-A,-B,-DRB1的单倍型可作为HLA全相合无关供者? 移植中GVHD风险预测的指标;?MHC单倍型的研究有助于发现新的移植免疫相关基因;?MHC单倍型的研究有助于提高骨髓捐献者库的供者多样? 性,指导最佳供者选择;РHLA配型与移植的焦点问题РCurr Opin Hematol 2008;15:549-554;?Thomas' Hematopoietic Cell Transplantation ?Stem Cell Transplantation(fourth edition2008)