ICU获得性重症多发性神经肌病

ry axonal motor and sensory neural disease ?Critical illness myopathy(CIM)?primary muscle disease – Occuring in critically ill patientsРICU获得性神经肌肉疾病РSepsis 并发症;Р200907РICU获得性神经肌肉疾病Р问题与危害:?使病情迁延,?延长带机时间?增加并发症?延长了ICU滞留时间?增加病死率(7倍)?和增加医疗费用РWitt NJ, Chest 1991; Tennila, Int Care Med 2000; Berek K, Intensive Care Med 1996; Bercker, Crit. Care Med 2005, Garnacho-Montero Crit Care Med 2005, Leijten FS, JAMA 1995Р200907РCritical illness polyneuropathy(CIP)РBoiton et al (1984) 首次描述:在sepsis和MOF患者中并发的一种非常普遍的神经病。?sepsis and MOF: 70-100%;?ARDS: 60%;?MV ≥ 7d : 25 ~ 58%; ?曾用名?critical illness neuromuscular disease?critical illness neuropathy?Acute respiratory failure neuropathyРBerek K, et al. Polyneuropathies in critically ill patients: a prospective evaluation. Intensive Care Med 1996;22: 849—55Р200907