ntinuousdistribution.Themainsymptomsaleabdominalpain,diarrheaandmucopurulentbloodyst001.Thisdiseaseoftenhasalongcourse,andiseasytorepeatedattackthatseriouslyaffectsthelifequalityofpatients,anization(WHO).Therefore,clarifyingtheetiologyandpathogenesisofthedisease,andsearchingfortheeffectivetherapyhasbeenoneoftheresearchhotspotinrecentyears.Animalmodelhasallimportantsignificanceforstudyingitsetiology,pathogenesis,therapymethod,researchanddevelopmentofnewdrug.Choosingtherightanimalmodelforresearchpurposesisessential.Thisstudymainlydiscussthemodeleffectofseveralchemicaldrug-inducedmodels,includingdextransulphatesodium(DSS),2,4,6-trinitrobenzenesulfonicacid(TNBS),oxazolone(OXZ)etc.monmethodsofchemicallyinducedcolitis.BestmodelmethodforthestudyOilpathogenesisandtreatmentcontinuallywillbechosen.7
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