mical staining were performed to test the role of Fascin-1 in the proliferation of A549 cells invivo.РResultsРFascin-1 protein exhibited and located in the cytoplasm and cellular membrane of positive cells diffusely or locally by immunostaining with a rate ofР83.67%(82/98) in NSCLC, which was largely confined to the lung cancer cells,Рthe endothelial cells of the microvessels and dentritic cells, but in the normal lung, the non-neoplastic bronchial and alveolar epithelia cells were non-reactive for Fascin-1. There was no difference between gender, age and histological subtypes for the expression of Fascin-1(P> 0.05). However, the expresssion of Fascin-1 was significantly correlated with TNM staging and regional lymph node metastasis(P < 0.05). The rates of Fascin-1 expression of NSCLC were
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