差?组织病理学和/或影像学HRCT表现为普通型间质性肺炎(UIP)РAm J Respir Cri Care Med.,2011,187,788-824Р0Р50Р100Р150Р200Р250Р300Р45-54Р55-64Р65-74Р75+РMaleРFemaleР0Р20Р40Р60Р80Р100Р120Р45-54Р55-64Р65-74Р75+РMaleРFemaleРPrevalenceРIncidenceРPer 100,000РPer 100,000РIncidence: > 30,000 patients/year? Prevalence: > 80,000 current patients? Age of onset: most 40–70 years? Two-thirds > 60 years old at presentation? Males > femalesРATS/ERS. Am J Respir Crit Care Med. 2000;161:646-664.?Raghu G, et al. Am J Respir Crit Care Med. 2006;174:810-816.Р美国流行病学资料РIPF/UIPРAm J Respir Cri Care Med.,2011,187,788-824РIPF临床表现РSubjected to external reviewР成人?不能解释的劳累型呼吸困难?咳嗽?双肺底吸气爆裂音(Velcro)?杵状指РIPF诊断标准Р排除其它已知原因导致的ILD (如:环境和职业导致的肺病,CTD-ILD,和药物性肺病等)。?在没有外科肺活检资料条件下,胸部HRCT呈现典型的UIP表现。?有外科肺活检资料条件下,胸部HRCT和病理均符合UIP表现。РSubjected to external review