Venous Thrombosis Pulmonary Embolism深静脉血栓形成和肺栓塞ppt课件

y.?1 in 100 in people over 80yrsРAm J Prev Med. 2010 Apr;38(4 Suppl):S502-9. doi: 10.1016/j.amepre.2010.01.010.РWhy is is important to recognize DVT/PE?РHigh MortalityР10 to 30% of people with PE will die within one month of diagnosis.?Sudden Death is the first presentation in 25% of patients with PEРAnd High Morbidity…Р50% will have long plications (post-thrombotic syndrome)?33% will have recurrence within 10 yearsРPathoPhysiology of VTEРVirchow’s TriadРRudolph Virchow, 1858РRisk FactorsРInherited Thrombophilia?Factor V Leiden mutation?Prothrombin gene mutation?Protein S deficiency?Protein C deficiency?Antithrombin (AT) deficiency?DysfibrinogenemiaРAcquired Disorders?Malignancy?Presence of a central venous catheter?Surgery?Trauma?Pregnancy/OCP/HRT ?Drugs ?Immobilization?Congestive failure