松药 depolarizing Muscle relaxants?琥珀胆碱(司可林,inylcholine, scoline)?Dose:1-1.5mg/kg IV?Onset of action: within 60 seconds?Duration of action: 3-5 minutes?Metabolism: by plasma cholinesterase?Uses?To facilitate endotracheal intubation in full-stomach patients?To maintain paralysis for short proceduresР肌肉松弛药? Muscle relaxantsР去极化肌松药 depolarizing Muscle relaxants?琥珀胆碱(司可林,inylcholine, scoline)?Adverse effects?Muscle pains?Bradycardia?Hyperkalaemia?Increase in intracranial pressure and intraocular pressure?Prolonged action?Malignant hyperthermiaР肌肉松弛药? Muscle relaxantsР非去极化肌松药 non-depolarizing Muscle relaxants?常用药物?阿曲库铵 Atracurium?维库溴胺 Vecuronium?潘库溴胺 Pancuronium?哌库溴胺 pipecuronum?Uses?To facilitate endotracheal intubation ?To maintain paralysis during anesthesia and in the ICU?拮抗药:新斯的明 neostigmine