卒中发病同时发生4;Р1Bogousslavsky J. Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology 1988; 38: 837–48.?2Widar M.Long-term pain conditions after a stroke. J Rehabil Med 2002;34: 165–70.?3Bowsher D. Stroke and central poststroke pain in an elderly population. J Pain 2001; 2: 258–61.?4Gyanendra Kumar. Central post-stroke pain: Current evidence. J Neurological Sci, 284 (2009) 10–17.РClinical characteristics of CPSPР与病变大小、损伤侧无显著相关性;与部位( brainstem or thalamus)有一定相关性;?自发痛与诱发痛并存(spontaneous or evoked);?疼痛分布范围可大可小(the hand, to one side of the body) ;?受部位影响感觉的“阴性”与“阳性”体征并存(“negative” and “positive” sensory events);?痛觉超敏(Allodynia)、痛觉过敏(Hyperpathia)与感觉迟滞(Dysesthesias)并存;?卒中后不同时期均可发生,90%有客观感觉异常;РKumar. Anesth Analg 2009;108:1645–57РKumar B,et al. Anesth Analg. 2009,May;108(5):1645-57