卵巢癌化疗新进展-中山大学肿瘤医院

期卵巢癌早期卵巢癌 Medical Oncology: prehensive review. Medical Oncology: prehensive review. . textbook textbook 低危低危高危高危(5– 10% 复发率) (30 – 40% 复发率) Stage IA or IB Stage IA or IB Stage IC Stage IC Grade 1 (or 2) Grade 3 Clear cell cancer 高危早期卵巢癌高危早期卵巢癌 1. 1. Young SGO 2003 Young SGO 2003 2. Young RC. 2. Young RC. Semin Semin Oncol Oncol 27 (3):8-10., 2000 27 (3):8-10., 2000 3. ICON-1, EORTC-ACTION: J 3. ICON-1, EORTC-ACTION: J Natnl Natnl Can Inst. Vol. 95, No. 2, January 15, 2003 Can Inst. Vol. 95, No. 2, January 15, 2003 4. 4. Mannel Mannel et al. et al. GOG-175 protocol, GOG-175 protocol, .gov .gov GOG GOG –– 157 157 1,2 1,2 辅助化疗的随机临床试验: 3 vs 6 疗程紫杉醇+ 卡铂结果 6个疗程进展危险性降低了 33% 生存率无改善 Action & Icon Action & Icon 3 3随机临床试验无立即化疗 vs 立即化疗结果立即化疗生存率提高 8% vs 复发时化疗(82% vs 74%)