ddle third of rectum ? Colon/Rectum without serosa – Posterior ascending – Posterior descending – Lower third of rectum (rectal ampulla) Layers of Colon Wall Serosa Mucosa Submucosa Muscularis propria Subserosa Graphic from CS mittee Training Materials Colon Wall Anatomy ? Non-invasive tumors – Intraepithelial tumors do not extend beyond the epithelium of the mucosa ? Invasive tumors confined to the mucosa – Intramucosal tumors invade the lamina propria but not beyond ? Locally invasive tumors – Through the lamina propria into the muscularis mucosa – Through the wall indicates involvement of subserosa Colon Wall Anatomy ? Terms defining invasion through serosa – To, into, or through serosa – Invasion of or through serosa – Extensively involving serosa – Tumor on serosal surface