aills.tly,most ofCysLT receptor antagonists are CysLTl 5 浙江_人学博士学位论文 3.CysIJl龇ptor锄tagoIlist pmnlukast attenuates thene啪nal damage andinhibits theast眦”e proIiferation.11lesefmdin萨funIlerc0Ilfi响that CysLTl recep衄mediates acute neumnal damag蓐柚dsub删e/chmnic器trogIiosis after focalcerebralisch锄ia. CysUl feceptor may be alsomediate acute neurional damage and subacu把/ehfonic as蜘四iosisIbut thismediation needs lobeclarified. 4.Inno册a】fa￡b豫in,CysLl、p0断is exp删话ed iⅡ|he chofoid plexIls and endothelial celIs.CysⅡ’2 rec印tof iscxprcssed lls,neufons and astroglial cellsaround ventricle,%peciany inthalamus and hypothalamus neaf to vent—de.T1lese矗ndiIlgs indicatetllalbothCys L,rl andCysLrr2 receplors may reIate to cerebralspinal fluidciFclllation,andCysL疋receptor may beinvolved inneumendocfi衄1 modulatjon. 9
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