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药代动力学与新药的研究综述

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barrierfunctinnandrestrictsantiepilepticdrugactivity.JPharmacolExpTher,2003,306:124^131.NagashigeMetal.BasalmembranelocalizationofMRP1inhumanplacentaltrophoblastPlacenta,2003,24:95广958.Shibataetal.Aconvenientinvitroscreeningmethodforpredictinginvivodrugmetabolieclearanceusingisolatedhepatocytessuspendedinserum.DrugMetabDispos,2000,8:1518、1523.RingBJetal.IdentificationofthehumancytochromesP450responsibleforatomoxetinemetabolism.DrugMetabDispos,2002,30:319~323・王青秀,吴纯启,廖明阳。细胞色素卩450的诱导机制及其筛选方法的研究进展。国外医学•药学分册,2003,30:43~46。YuehMF,KawaharaM,RaucyJ.Cell-basedhigh-thro)^ghputbioassaystoassessinductionandinhibitionofCYP1Aenzymes.ToxicolInVitro,2005,19:275^287・CrivoriP,putationalapproachesforpredictingCYP-relatedmetabolismpropertiesinthescreeningofnewdrugs.EurJMedChem,2006,41:795~808.MSX空间完美搬家到新浪博客!

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