877.[5]VandenBergheG,WilmerA,HermansG,etal.IntensiveinsulintherapyinthemedicalICU[J].NEnglJMed,2006,354(8):449-461.[6]BrunkhorstFM,EngelC,BloosF,etal.Tntensiveinsulintherapyandpentastarchresuscitationinseveresepsis[J]・NEnglJMed,2008,358(6):125-139.[7]TheNICE-SUGARStudyInvestigators・Intensiveversusconventionalglucosecontrolincriticallyillpatients[J]・NEnglJMed,2009,360(3):1283-1297.[8]TheCOIITSSStudyInvestigators.Corticosteroidtreatmentandintensiveinsulintherapyforsepticshockinadults:arandomizedcontrolledtrial[J].JAMA,2010,303(6):341-348・[9]ClaytonSB,MazurJE,CondrenS,etal.Evaluationofanintensiveinsulinprotocolforsepticpatientsinamedicalintensivecareunit[J].CritCareMed,2006,34(11):2974-2978.[10]NasrawaySA.Sittingonthehornsofadi1emma:ontrol[J].CritCareMed,2007,35(7):2435-2437.(收稿日期:2013-05-25)