e encephalopathy. Ataxia. The loss of appetite , metallic taste in the mouth, gingival lead line, abdominal cramps, nausea, vomiting, diarrhea. Hematopoietic system in the low hemoglobin, normal red blood cell-cell or small cell anemia, red blood cell stippling appears, work erythrocytosis. Other diseases are tРoxic hepatitis, hepatomegaly , jaundice, and kidney damage have also resulted in oliguria , anuria , hemoglobinuria , causing nephritis or renal atrophy, can also cause myocardial injury, congestive heart failure appear [14].РChapter 2 Materials and Methods Р2.1 Experimental materials РLasting whitening liquid foundation market РXue Yan whitening moisturizer marketРEight glasses of water nutrition moisturizing cream market РJohnson & Johnson baby nourishing moisturizing cream market