髓病灶=1个幕下病灶;1个脊髓增强病灶=1个脑部增强病灶;S区域至少2个区域有≥1个T2病灶:●侧脑室旁●近皮质区●幕下●脊髓注:DIS诊断标准中不需要钆增强病灶;若患者有脑干或脊髓综合征,其责任病灶不在MS病灶数统计之列*颅脑MRI特征病灶多发,大小数毫米到2厘米最多见,较大病灶可呈“假肿瘤征”或弥漫分布病灶;最常见部位为两侧脑室旁,病灶长轴与脑室“垂直”分布;其次为胼胝体、颞叶、脑干、小脑、脊髓,亦可位于近皮质(累及U形纤维),单发病灶幕下多见;急性病灶有膨胀感,T1WI表现低或略低信号;T2WI表现“核心+晕环”征象。增强后为病灶周围环形/半环形强化或斑点/斑片状强化。稳定期病灶可无强化,新老病灶可同时存在。慢性病灶有收缩感,分布于两侧脑室旁或散布于脑室旁、皮质下、脑干等部位,信号均匀。*TypicalforMSinthiscaseis:Involvementofthetemporallobe(redarrow)Juxtacorticallesions(greenarrow)-touchingthecortexInvolvementofthecorpuscallosum(bluearrow)Periventricularlesions-touchingtheventricles*TypicalfindingsforMSasseeninthiscaseare:Multiplelesionsadjacenttotheventricles(redarrow).Ovoidlesionsperpendiculartotheventricles(yellowarrow).Multiplelesionsinbrainstemandcerebellum.*JuxtacorticallesionslocatedintheU-fibersarealsoveryspecificforMS*
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