s: Parkinson’s disease, multiple sclerosis, and stroke. J Neurol Neurosurg Psychiatry,2005,76;48-52.?5. Lambert M, Robertson M. Depression in epilepsy: etiology, phenomenology and treatment. Epilepsia,1999,40(suppl 10):S21–S47.?6. Gaitatzis A,Trimble MR,Sander JW. The orbidity of epilepsy. Acta Neurologica Scandinavica,2004,110:207-220.Р流行病学Р原发性头痛伴抑郁焦虑障碍1~2Р原发性头痛门诊患者调查发现27%的患者有中-重度抑郁,其中偏头痛人群为17.1%、转化型偏头痛为36.1%、紧张型头痛(TTH)为28.3%;?偏头痛患者终身的抑郁障碍患病率约为30%~80%,是普通人群的3-4倍。同时,易有惊恐和强迫等焦虑障碍;?有先兆的偏头痛和转化型偏头痛者的伴发率更高。频发型和慢性TTH者抑郁焦虑障碍的伴发率可达2/3;?青少年慢性头痛者调查,有抑郁障碍30%(抑郁症21%)、焦虑障碍36%、高度自杀危险者20%Р1. Radat F,Swendsen J. orbidity in migraine: a review. Cephalalgia,2005,25:165-178.?2. Wang SJ,Juang KD,Fuh JL,et al. orbidity and suicide risk in adolescents with chronic daily headache. Neurology, 2007,68:1468–1473.
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