nd microarchitechtural deterioration of bone tissue, with a consequent increase bone fragility and susceptibility to fracture.РAnonymous, Am J Med 1993;94:646)Р骨质疏松的定义-NIHР骨质疏松是一种全身性骨病,其特点是骨强度减弱,增加骨折的危险性. 骨强度是骨密度和骨质量的综合反映。?A skeletal disorder characterized promised bone strength predisposing to an increased risk of fracture. Bone strength reflects the integration of two main features:bone density and bone quality.РNIH consensus development panel. JMA 2001; 285:785Р骨质疏松的定义-临床Р有“脆性骨折”。即由于轻微外伤,如从站立或更低的高度跌倒。?Presence of a “fragility” fracture. Fracture due to minimal trauma, such as after fall from standing height or less.Р骨质疏松的定义-骨密度РWHO专家组根据白人绝经后妇女骨密度测量数据制定了骨质疏松骨密度定义:?T值-2.5SD为骨质疏松(Osteoporosis)。?T值-2.5SD 但<-1SD为骨量减少(Osteopenia)РKanis JA. Et al. J Bone Miner Res 1994;9:1137Р成人骨结构Р骨质疏松的形态表现