nee Shannon M. Wolfe The Problem ? Young active patients with articular cartilage defects! – Which defects progress to OA ? – Which defects are symptomatic ? – How do we most effectively treat these defects? The Biology ? Physiologic role of articular cartilage – Minimize stresses on the subchondral bone – Reduces friction on the weight bearing surface ? Critical in proper joint function Goals of Treatment ? Restore integrity of load bearing surface ? Obtain full range of motion ? Obtain pain free motion ? Inhibit further degeneration Treatment Considerations ? Age of the patient ? Defect size ? Knee stability ? Knee alignment ? Level of activity Partial Thickness Defects ? Articular cartilage lacks the capacity to repair structural damage ? Progresses when exposed to mechanical wear