lls T4 90% T3 10% TSH Subacute thyroiditis – pathology Multinucleated giant cell Thyrotoxicosis – Signs/Symptoms ? Nervousness ? Sweating ? Heat intolerance ? Palpitations ? Tachycardia ? Fatigue/weakness ? Weight loss ? Dyspnea ? Increased/decreased appetite ? Goiter ? Skin changes ? Tremor ? Atrial fibrillation ? Splenomegaly ? astia ? Eye pain, diplopia, eye swelling, lid lag, proptosis Thyrotoxicosis - differential ? Graves ’ disease ? Toxic adenoma (solitary) ? Toxic multinodular goiter ? Subacute thyroiditis ? Hashimoto ’ s thyroiditis (transient hyperthyroid phase) ? Thyrotoxicosis factitia ? Postpartum ? Struma ovarii 卵巢甲状腺瘤? Metastatic thyroid carcinoma 转移性甲状腺癌? Hydatidiform mole 葡萄胎,水泡状胎块? TSH-secreting pituitary tumor ? Pituitary resistance to triiodothryonine and thyroxine