Univer- erature or of individual patient data? Lancet. 1993; intervention efficacy reported in meta-analyses? Lan-Рsity of Calgary, Calgary; Sander Greenland, DrPH, Cstat, 341:418-422. cet. 1998;352:609-613.РMA, MS, University of California, Los Angeles; Rich- 26. Steinberg K, Smith SF, Lee N, et al. Comparison 51. Berlin JA, Colditz GA. The role of meta-analysisРard Horton, MBBCh, MD, Lancet, London, England; of effect estimates from a meta-analysis of summary in the regulatory process for foods, drugs, and de-РDiana Petitti, MD, MPH, Southern California Kaiser data from published studies and from a meta- vices. JAMA. 1999;281:830-834.Р2012 JAMA, April 19, 2000—Vol 283, No. 15 ©2000 American Medical Association. All rights reserved.Р Downloaded from Fudan University on December 22, 2009