ffect of bear guts gutta on rabbit derat- burn and conjunctitisw as better than di- bearРguts gutta and alficetin eyedrop s (P < 0. 05). Its effect on co rneal nebula w as better than surnam e azulene serenity eyedrop sРand di- bear guts gutta (P < 0. 01). Scanning electron m icro scope w as used to observe the therapeutical effects of bear gutsРgutta on co rneal nebula. T he results show ed the co rneal ep ithelial cells renew ed mo re quick ly than the contro l group s. F iveРmonth s later, the co rneal ep ithelial m icrovilli arrayed regularly, similar to the no rm al ultrastructure. T hese results indicatedРthat bear guts gutta could recover the co rneal nebula ep ithelial cells to the no rm al structure.Р Key words: bear guts gutta; kerat- burning; co rneal nebula; therapeutic effects