ntphotosensitizersРthatareintheclinicalapplicationshasledtotheactivedevelopmentofthenewgenerationofphotosensitizer.РAnotherapproach-peptideconjugation-toenhancethetissuespecificityofphotosensitizerswerereviewed.ThecellРratingpeptides,vasculaturetargetingpeptides,andpeptidestargetingcellsurfacereceptorswerereviewed.РThecurrentresearchindicatesthattheeffectivenessofpeptideconjugationtoconferthetissuespecificitytoРphotosensitizers.РKeywords photodynamictherapy,photosensitizer,cancer,targeted,peptideРDOI: 10.3724/SP.J.1206.2009.00080Р*ThisworkwassupportedbygrantsfromHi-TechResearchandDevelopmentProgramofChina(2006AA02A313)andTheNationalNaturalScienceРFundsforDistinguishedYoungScholar(30625011).Р**Correspondingauthor.Tel:86-591-83704996,E-mail:mhuang@fjirsm.РReceived:February15,epted:May18,2009