e method of concealment is not described or not described in sufficient detail to allow a definite judgement – for example if the use of assignment envelopes is described, but it remains unclear whether envelopes were sequentially numbered, opaque and sealed.Р РBLINDING OF PARTICIPANTS AND PERSONNELРPerformance bias due to knowledge of the allocated interventions by participants and personnel during the study.РCriteria for a judgement of ‘Low risk’ of bias.РAny one of the following:РNo blinding or plete blinding, but the review authors judge that the e is not likely to be influenced by lack of blinding;РBlinding of participants and key study personnel ensured, and unlikely that the blinding could have been broken.РCriteria for the judgement of ‘High risk’ of bias.РAny one of the following: