对甲苯磺酰氯的合成研究

潮洪.医药中间体制备手册[M].北京:化学工业出版Р社,2001,44卜442.Р[5]PeterTonne,eta1.1一Alkyl一2一Chloro一5一Nitrobenzene一4一РSulfonicAcids[P].us442760Q.Р[6]唐培望.精细有机合成化学及工艺学[M].天津:天津大学出版社,Р1999,】20-】35РStudySynthesisofp——ToluenesulfonylChlorideРHAOyan—xiaJ.SUYan-xi0Р(1.ShijiazhuangVocationalTechnologyInstitute,ShiJiazhuang050081,China:2.CollegeofChemistry,HebeiNormalРUniversity,ShiJiazhuang05009I,China)РAbstract:p-To1uenesu1fonylchloridewassynthesizedbytakingtolueneasrawmateria1.Inthereactionofsulfonation,Рtheazeotropicwaterremoving,sulfuricacidwasusedassulfonatingagent.Inthereactionofchlorination,carbonРtetrachloridewasusedasagent,andchlorinegasaschlorinatingagent.ByUSingthistechnique,theuseratioofРsulfuricacidwashigher,andoperatingcostwaslower.РKeywords:o-toluenesu1fonylchloride:toluene:SUlfonation:chlorinationР一HР一Р∞