rs within 5 days of stroke onset.РDeep perforating artery infarct was more frequently associated with PMD (35.8%) compared with large artery disease (27.3%) and cardioembolism (5.3%). РMultiple logistic analysis found that deep perforating artery infarct was independently associated with PMD. Deep perforating artery infarct is the major cause of PMD.РSSSI(孤立皮层下小梗死)РNeuroimaging Markers for END in SSSIРEarly neurological deterioration (END) occurs in ≥20% of single small subcortical infarctions.?Patients with relevant artery stenosis and branch atheromatous lesions had significantly higher odds of exhibiting END.РBranch atheromatous disease and its association with progressive motor deficitsРBADРBADР亚洲国家多发,研究集中于日本、韩国;?早期END比例较高;?缺乏统一定义,目前诊断主要依赖梗死灶分布、大小、形态;?高分辨MRI研究较少;?与大动脉粥样硬化性比较,危险因素无显著差异。