内科学：Chapter 15 Hepatocellular Carcinoma

in B1??  Drinking Water Pollution: Algae toxin? could contaminate water sources??  Chemical carcinogens : nitrite, organic ? chlorine pesticides ??  Parasite: liver flukeРEtiology and pathogenesisРРPathology?  Morphological typing?  Block type (>5cm)?  Nodular type (＜ 5cm) ?  Diffuse type?  Small hepatocarcinoma (＜3cm)?  Cell classification?  Hepatocellular??  Bile duct cell typeРРРРР metastasis? 1. Intrahepatic metastasis?? 2. Extrahepatic metastasis ? （1）Hematogenous metastasis? （2）Lymphatic metastasis? （3）implantation metastasisРPathologyРРSubclinical hepatocellular carcinoma:? Without any signs and symptoms? AFPРclinical manifestation