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T细胞亚群

上传者:幸福人生 |  格式:ppt  |  页数:53 |  大小:0KB

文档介绍
on the history of antigen encounter and the stage of T cell activation.РРРРРNaive T cellsРEffector T cellsРMemory T cellsРMigrationРPreferentially to peripheral lymphoid tissuesРPreferentially to inflamed tissuesРPreferentially to inflamed tissues, mucosal tissuesРFrequency of cells responsive to particular antigenРVery lowРHighРLowРEffector functionsРNoneРCytokine secretion; cytotoxic activityРNoneРCell cyclingРNoРYesР+/-РSurface protein expressionРРРРHigh-affinity IL-2 receptorРLowРHighРLowРPeripheral lymph node homing receptor (L-selectin, CD62L)РHighРLowРLow or variableРAdhesion molecules: integrins, CD44РLowРHighРHighРChemokine receptor: CCR7РHighРLowРVariableРMajor CD45 isoform (humans only)РCD45RAРCD45ROРCD45RO; variableРMorphologyРSmall; scant cytoplasmРLarge; more cytoplasmРSmall

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