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绿色荧光蛋白gfp的研究进展及应用

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42. [16]HansonGT,McAnaneyTB,ParkES,etal.Greenfluorescentprotein variantsasratiometricdualemissionpHsensors.1.Structural characterizationandpreliminaryapplication[J].Biochemistry,2002, 41:15477-15488. [17]JayaramanS,HaggieP,WachterRM,etal.Mechanismandcellular applicationsofagreenfluorescentprotein-basedhalidesensor[J].J BiolChem,2000,275:6047-6050. [18]YuR,HinklePM.Rapidturnoverofcalciumintheendoplasmic reticulumduringsignaling:studieswithcameleoncalciumindicators[J]. JBiolChem,2000,275:23648-23653. [19]YukIHY,WildtS,JolicoeurM,etal.AGFP-basedscreenfor growth-arrested,binantprotein-producingcells[J].Biotechnol Bioeng,2002,79:74-82. [20]GonzalezJE,NegulescuPA.Intracellulardetectionassaysforhigh- throughputscreening[J].CurrOpininBiotechnol,1998,9(6):624- 631. (收稿日期:2009-01-10) 86 生物医学工程研究第28卷

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