echnology ,the life cycle and the development time of product is shortened ,the uncertainty of business environment w hich enterprises is increasing .T his paper presents a new form of en‐ terprise a business - led cooperation leading technology research institute ,analyzes the development train of thought and structure of strategic positioning ,enterprise leading technical institute of industry ,the final design of the operating mecha‐ nism of the corresponding .A s a bridge betw een industry and technology "bridge" and "link" ,solve the problem s of the in‐Рnovation of industrial cluster ,effectively enhance the petitiveness of enterprises innovation ability and industry .РKey Words :Industrial Technology Research Institute ;L eading Enterprises ;Integ rated Innovation ;M anagement M ode