Chem,2004, 279(25):26533 -26539. Р [15] Li J, Jiang K, Zhao F. Oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microRNA?29b and downregulating matrix metalloproteinase?2 expression[J].Mol Med Rep, 2015, 12(4):5369-5374. Р [16] Masoumi-Moghaddam S, Amini A, Wei AQ, et al. Vascular endothelial growth factor expression correlates with serum CA125 and represents a useful tool in prediction of refractoriness to platinum-based chemotherapy and ascites formation in epithelial ovarian cancer[J].Oncotarget, 2015, 6(29):28491-28501. Р [17] Desmeules P, Trudel D, Turcotte S, et al. Prognostic significance of TIMP-2, MMP-2, and MMP-9 on high-grade serous ovarian carcinoma using digital image analysis[J]. Hum Pathol, 2015, 46(5):739-745.