ug.?Rejection of the transplant remained a major obstacle until the late 1970s.РРOther organ transplantations followedРIn 1963 James Hardy transplanted the first lung.?In 1966 there was the first simultaneous pancreas/kidney transplantation and 1 year later the first successful liver transplantation followed.РРРThe first successful human heart transplantation was performed on 3 December 1967 by Christian Barnard. The recipient initially recovered but subsequently died of pseudomonas pneumonia 18 days later.РРРProgress in histocompatibility typing, immunosuppressive therapy, and organ preservation and accumulation of clinical experience gradually resulted in further improvement in transplantation that allowed successful replacement of not only failing kidneys but other vital organs as well.