神经元型一氧化氮合酶(nNOS) 与疼痛

urosci,2003,17(7):1384-92inducedpaininmice.BrainRes,2009,1289:14-21[25]Guan,Y,YasterM,RajaSN,etal.icknockoutand[33]LiuW,WangCH,CuiY,etal.Inhibitionofneuronalnitricpharmacologicinhibitionofneuronalnitricoxidesynthaseoxidesynthaseantagonizesmorphineantinociceptivetoler-attenuatenerveinjury-inducedmechanicalhypersensitivityancebydecreasingactivationofp38MAPKinthespinalinmice.MolPain,2007,3:29microglia.NeurosciLett,2006,410(3):174-7[26]JinXG,HeSQ,YanXT,etal.Variantsofneuralnitricoxide[34]YamazakiMK,ChibaK,MohriT,etal.Activationofthesynthaseinthespinalcordofneuropathicratsandtheirmitogen-activatedproteinkinasecascadethroughnitricoxideeffectsonnuclearfactor-κB(NF-κB)activityinPC12cells.synthesisasamechanismofneuritogeniceffectofgenipininJPain,2009,10(1):80-9PC12hcells.JNeurochem,2001,79(1):45-54