et al. COX-2 polymorphisms and colorectal cancer risk: a strategy for chemoprevention. European journal of gastroenterology & hepatology, 2010. 22(5):607-613. Р [12] Piranda, D. N, Festa-Vasconcellos, J. S, Amaral, L. M, et al. Polymorphisms in regulatory regions of cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study. BMC cancer, 2010. 10: 613. Р [13] 许东奎, 张雪梅, 赵平等. COX-2 基因启动子区单核苷酸多态与肝癌遗传易感性的关系. 中华肝胆外科杂志, 2009. 14(12): 840-843. Р [14] Chang, W.S, Yang, M.D, Tsai, C.W, et al. Association of Cyclooxygenase 2 Single-Nucleotide Polymorphisms and Hepatocellular Carcinoma in Taiwan. Chinese Journal of Physiology, 2012. 55(1): 1-7. Р 1、作者简介:李永强,男,副主任医师,硕士学位,硕士生导师,主要从事肿瘤内科的临床诊治和研究工作Р 2、本文为广西卫生厅重点科研课题相关论文。前列腺素内过氧化物合成酶2基因单核苷酸多态性与原发性肝癌预后关系研究,2008年07月至2011年07月。合同编号重200869