自身免疫病的免疫学检验检查

ease1自身抗体临床应用;1)协助自身免疫性疾病诊断.2)协助判断病情、疗效和预后。3)协助进行不同疾病的鉴别诊断4)用于各类疾病的免疫病理和机制研究及流行病学的调研。自身抗体是诊断自身免疫病五种主要依据(遗传倾向、性别和年龄、免疫抑制剂疗效和多器官发病)之一与自身免疫性疾病关系密切的自身抗体?自身免疫病标志性抗体MarkerofantibodiesAssociatedautoimmunediseasesAnti-dsDNAantibodiesSLEAnti-SmantibodySLEAnti-SS-BantibodySSAnti-centromereantibodyPSS,limitedformAnti-Scl-70antibodyPSS,diffuseformAnti-PM-SclantibodyPM/DMoverlapsyndromeAnti-JoantibodyPM/DMAnti-RNPantibody(hightiter)MCTDSMAAutoimmunehepatitis(typeI)LKM-1Autoimmunehepatitis(typeII)SLA/LPAutoimmunehepatitis(typeIII)AMA-M2PBCAFARAAnti-PR3antibodyWegener‘sgranulomatosisMarkerantibodiesofautoimmunediseases对流免疫电泳法(CounterimmunoelectrophoresisCIE)免疫扩散法(immunodiffusionassayID)间接免疫荧光法(indirectimmunofluorescenceassayIIF)酶联免疫吸附法(enzyme-linkedimmunosorbentassayELISA)免疫印迹法(ImmunoblotassayIB)自身抗体检测方法