ut colonization and brain development processes.Р6Р123РObjectivesР7Р123Р1.In this prospective, longitudinal study, the researchers tested whether the 1-year-old gut microbiome was associated with cognitive es at 1 and 2 years of age.?2.They hypothesized that infant gut microbiome samples would cluster into groups munity similarity and that cognitive ability would differ between clusters.根据群落相似性,肠道菌群样本可以聚类为不同的组,而聚类到不同组的婴儿可能具有不同的认知能力Р8Р123РMethodsР9Р123Р1. Study PopulationРRecruited 89 1-year-old infants (twins and singletons) from two prospective longitudinal studies of early brain development at the University of North Carolina at Chapel Hill.两项关于早期大脑发育的前瞻性、纵向研究?Exclusion criteria for the parent studies included fetal ultrasound abnormalities and major medical illness of the mother.Р10Р123