时,水疱下坠,乃因白细胞向下沉积。Р6.1、表皮内水疱Р(A) 细胞间连接溶解?(B) 病毒感染致表皮细胞气球样变,如varicella-zoster(水痘-带状疱疹病毒) ?带状疱疹herpes zoster 沿皮神经分布,串珠状的水疱。水疱中心凹陷,称为脐凹征。?轻压水疱,水疱向周围扩张并增大,称为Nikolsky征阳性。常见于寻常型天疱疮。РNikolsky's signР6.2、表皮下水疱РSubepidermal vesicles, as shown in the drawing (A), occur as a consequence of pathologic changes in the region of the dermal-epidermal junction. Subepidermal vesicles and bullae are seen in bullous erythema multiforme(大疱性多形红斑), porphyria cutanea tarda (迟发性皮肤卟啉病), epidermolysis bullosa(大疱性表皮松解症), dermatitis herpetiformis(疱疹样皮炎), and bullous pemphigoid(大疱性类天疱疮). ?The clinical photograph (B) demonstrates bullae in the latter condition. Some of them arise on normal and some on erythematous skin. Most of them are tense and filled with a serous or hemorrhagic fluid; some have collapsed and crusted.
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