ocessed in order?to be recognised by T cellsРYРTРT cell?responseРNo T cell?responseРNo T cell?responseРNo T cell?responseРNo T cell?responseРSoluble?native AgРCell surface?native AgРSoluble ?peptides?of AgРCell surface peptides of Ag presented by cells that express MHC moleculesРANTIGEN?PROCESSINGРAPCР抗原提呈细胞及抗原提呈Р掌握抗原提呈细胞的种类和特点Р1Р熟悉抗原的处理和提呈过程Р2Р了解非经典抗原提呈途径Р3РTable of ContentsР第一节抗原提呈细胞?(Antigen Presenting Cell, APC)?一、概念与分类**? (Definition & Classification) ?二、树突状细胞***? (Dendritic Cell, DC)?三、单核-吞噬细胞系统*? (Mononuclear Phagocyte System, MPS)?四、B细胞? (B lymphocyte)Р名称Р专职性APC?Professional APCР非专职性APC?non-Professional APCР靶细胞?广义APCРMHC分布Р组成性表达?MHC-II类分子Р诱导性表达?MHC-II类分子Р表达?MHC-I类分子Р细胞Р树突状细胞?巨噬细胞?B细胞Р内皮细胞?成纤维细胞?上皮细胞等Р所有有核细胞Р功能Р负责将抗原提呈给CD4+的Th细胞Р负责在一定条件下?将抗原提呈给?CD4+的Th细胞Р负责将抗原提呈给CD8+的CTL细胞Р抗原提呈细胞的分类
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