ay model illustrates key steps in homologous bination 2) Homologous bination is often initiated by double-stranded breaks in DNA. It is known that Spo11 generates double-stranded breaks in eukaryote. 3) RecBCD helicase/nuclease processes broken DNA molecules and generates a single-stranded end. 4) plex and Dmc1 specifically promotes branch migration in bacteria and eukaryotes, respectively. PART III: SHORT QUESTIONS ( CHOOSE FIVE QUESTIONS TO ANSWER) (6 points each) 1. What is the central dogma? 2. Compare the chemistry and mechanism of splicing of mon pre-mRNA introns and group I and group II introns. 3. Briefly describe or illustrate how an extracellular signal can alter intracellular gene expression. 4. What are the molecular mechanisms that keep the DNA replication error rate as low as