S behavioural activity in mice using actophotometer S depressant study using Porsolt’s forced swim pool test(使用中枢神经系统镇定剂、porsolt强迫游泳池测试法和actophotometer仪器,对一些选定的化合物在小白鼠中枢神经系统Р行为活动方面的影响进行评估). The results are presented in Tables 3 and 4 respectively(这些结果分别在表3和表4中列出).Р4. Computational parameter(计算参数)Р The pharmacophore pattern studies in which distance between the various groups postulated as essential for anticonvulsant activity were done on the 3D optimized structures using ACD freeware 3D viewer 8.04 version(药效团模式研究中,假设分子团之间的距离不同作为必不可少的抗惊厥活性因素,并使用免费的8.04版ACD三维浏览器进行三维优化). Along with this CLOGP for selected pounds were calculated by using Pallas demo version 3112 which was pared with the experimental Log p data of these pounds(使用Pallas demo 3112版本和疏水性参数(CLOGP)对选定的合成化合物进行了计算,然后测定对选定化合物进行P的测量).
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